U.S. Vice President JD Vance is traveling to Islamabad to join talks between the United States and Iran, scheduled to begin Saturday, aimed at achieving a lasting ceasefire in the Middle East. Before his departure, President Donald Trump told reporters that Iran’s nuclear program would be the main focus of the discussions and that no backup plan was necessary. He added that a good deal with Iran would mean the absence of nuclear weapons and claimed that regime change had already occurred in Iran.

Trump also said the Strait of Hormuz would reopen soon, though he noted the United States did not need it. He rejected reports that Iran might impose tolls on ships passing through the strait, saying Washington would not allow that. Meanwhile, an Iranian delegation including senior officials such as Parliament Speaker Mohammad Bagher Ghalibaf and Foreign Minister Abbas Araghchi has already arrived in Islamabad for the talks.

The discussions are expected to address Iran’s assets and the Lebanon ceasefire, though their duration remains uncertain, according to Trump.